Endocrine Abstracts

It is well established that the kisspeptins are the main activators of GnRH neurons and therefore essential for the onset of puberty and reproduction. Previous studies have suggested that kisspeptin neurons are possibly major targets of pro-inflammatory cytokines to regulate reproduction. SOCS (suppressor of cytokine signaling) are proteins that regulate, as it says, cytokines. They inhibit the transduction of intracellular effects caused by those molecules, once that cytokine...